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THE SCIENCE BEHIND OMNIA

Your body runs on micronutrients.Most people are running on empty.

This page exists because we believe an informed customer is our best customer. Before we tell you about Omnium, we want to show you the clinical data behind what your body needs — and what most people are missing.

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THE FOUNDATION

Your Body Runs Trillions Of Reactions Every Second.
Micronutrients Power Them.

Vitamins and minerals are the catalysts your body cannot produce in sufficient quantities on its own. Every enzymatic reaction, immune response, nerve signal, and cellular repair process depends on them. Without them, the body doesn't stop — it simply becomes less efficient. That slow decline looks like fatigue, brain fog, poor sleep, and the feeling that you're not quite operating at your best.

Vitamins

Organic compounds that regulate metabolism, immune function, and cellular repair. Fat-soluble vitamins (A, D, E, K) are stored in tissue. Water-soluble vitamins (C and all 8 B vitamins) must be replenished every day — your body cannot store them.

Minerals

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Inorganic elements — zinc, magnesium, selenium, copper, and others — that govern structural functions like bone density and biochemical functions like enzyme activation, electrical nerve signaling, and hormone production.

THE CLINICAL DATA

The numbers are impossible to ignore.

This isn't about fringe deficiencies or developing countries. National Health and Nutrition Examination Survey data — the most comprehensive nutritional health database in the US — paints a clear picture of what most Americans are missing.

1 in 3

Americans are at risk of at least one micronutrient deficiency — and 1 in 12 are deficient in two or more at the same time.

NHANES · n=15,030 · Pfeiffer et al., Am. J. Clinical Nutrition 2017 · PMC5537775 

95%

Most people lack Vitamin D. It supports immunity, inflammation, and heart health.

Reider et al., Nutrients 2020 · NHANES 2005–2016 · n=26,282

Three independent gaps. Three different systems. All addressed in your daily Omnium packets. 
See the full clinical research →

90%

Low Omega 3 intake. 70 to 100mg daily. 250 to 500mg recommended.

NHANES 2003–2008 · n=24,621 · Framingham Cohort, Am. J. Clinical Nutrition 2021

48%

Consume inadequate magnesium. Cofactor for 300 plus enzymatic reactions including ATP energy production, sleep regulation, and DNA repair.

NHANES 2013–2016 · NIH Office of Dietary Supplements 2024

THE FOUNDATION

What happens when your foundation is missing.

The more common problem isn't severe deficiency — it's insufficiency. Levels that aren't low enough to show up on a standard blood test, but low enough to meaningfully affect how you feel and function every single day.

Persistent
Fatigue

B vitamins, iron, magnesium, and CoQ10 are all required for cellular energy production. Insufficient levels leave your mitochondria unable to generate ATP efficiently — no matter how much sleep you get, you feel drained.

Related: B-Complex · Magnesium

Brain Fog &
Low Mood

Folate, B12, zinc, and omega-3s are essential for neurotransmitter synthesis and myelin production. Without adequate levels, cognitive sharpness, focus, and emotional regulation all suffer — often written off as stress or aging.

Related: B-Complex · Omega-3

Weakened
Immunity

Vitamins C, D, A, and zinc are among the most critical nutrients for immune defense. Low levels impair the production and function of immune cells, leaving you more susceptible to infection and slower to recover.

Related: Vitamin C · ADEK ·

Trace Minerals

Bone &
Cardiovascular Risk

Vitamin D3 and K2 work together to regulate calcium — ensuring it deposits in bone rather than arteries. Without both, you can have adequate calcium intake and still experience bone loss and arterial calcification simultaneously.

Related: ADEK (D3 + K2)

Poor Sleep
& Recovery

Magnesium activates GABA receptors — the primary inhibitory neurotransmitter system responsible for calming the nervous system and enabling deep sleep. Deficiency is one of the most underrecognized contributors to insomnia and poor recovery.

Related: Magnesium Glycinate

Accumulated Cellular Damage

Selenium, vitamin E, vitamin C, and zinc are all critical antioxidants that neutralize free radicals before they damage DNA, proteins, and cell membranes. Long-term insufficiency accelerates biological aging at the cellular level.

Related: Trace Minerals · Vitamin C · ADEK

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THE CLINICAL PROOF

Does taking a supplement actually make a difference?

The same NHANES dataset that documented the deficiency gaps also studied what happened when people supplemented. The findings are unambiguous.

Without supplementation

95%

inadequate Vitamin D from food alone

84%

inadequate Vitamin E intake

46%

inadequate Vitamin C intake

With daily supplementation

65%

Vitamin D inadequacy — a 30 percentage point reduction

60%

Vitamin E inadequacy — a 24 point reduction

33%

Vitamin C inadequacy — a 13 point reduction

The same peer-reviewed study found that supplementation meaningfully closed every documented nutrient gap — reducing inadequacy across all five key immune-supporting nutrients measured. The researchers concluded that public health measures should ensure adequate intake given the long-term and widening nature of these gaps. This is precisely what Omnium was built to do.

NHANES 2005–2016 · n=26,282 · Reider et al., Nutrients 2020 · PMC7352522

THE SCIENCE OF ABSORPTION

Getting nutrients into the capsule is easy. Getting them into your cells is where most supplements fail.

Bioavailability is the percentage of a nutrient that actually reaches your bloodstream and tissues. It is determined by the form of the ingredient, how it's delivered, and your individual biology. Most supplement companies optimize for label claims. Omnium optimizes for absorption.

1

Ingestion

The capsule dissolves. The ingredient is released into the stomach and small intestine.

2

Absorption

The nutrient crosses the intestinal wall. Form determines how efficiently this happens the difference between 4% and 80%.

3

Conversion

Some nutrients must be converted to their active form before the body can use them. Genetic variants can block this step entirely.

4

The nutrient reaches target tissues and performs its function. This is the only step that actually matters.

Cellular Use

CHELATION

80%

vs ~4% for oxide form

Why Albion® chelated minerals absorb at 20× the rate of standard mineral forms

Minerals in their inorganic form — oxide, sulfate, carbonate — are positively charged ions that the gut struggles to transport across the intestinal wall. They also compete with each other for the same absorption pathways and bind to phytates and oxalates in food, becoming insoluble and passing through unused. Albion® chelation solves all three problems simultaneously: each mineral is covalently bonded to two glycine amino acids, creating a stable, electrically neutral molecule that the body transports via dedicated amino acid absorption channels — bypassing mineral competition and phytate binding entirely. The result is dramatically superior bioavailability, with none of the GI side effects of unabsorbed minerals drawing water into the colon.

Albion® is a registered trademark of Balchem Corporation · Multiple peer-reviewed absorption trials on file

GENETICS

40%

carry MTHFR C677T variant

Why the folate in most supplements may work less efficiently for nearly half the population

Why the folate in most supplements may work less efficiently for nearly half the population

Folic acid — the synthetic form of folate used in most supplements and fortified foods — must be converted by an enzyme called MTHFR before your body can use it. An estimated 30–40% of people carry variants of the MTHFR gene (C677T) that reduce this enzyme's efficiency, with homozygous carriers experiencing up to a 70% reduction in conversion capacity. For these individuals, taking folic acid means meeting the label requirement while potentially remaining functionally insufficient at the cellular level. Omnium uses 5-Methyltetrahydrofolate (5-MTHF) — the already-converted, biologically active form of folate that bypasses the MTHFR conversion step entirely, regardless of your genetic profile.

Estimated 30–40% MTHFR C677T prevalence · gnomAD global allele frequency 30% · Heterozygous: ~35% reduced activity · Homozygous: up to 70% reduced activity

LIPID SOLUBILITY

3.6×

better membrane crossing

Why Benfotiamine reaches nerve tissue that standard Thiamine cannot

Standard Thiamine HCl dissolves easily in the gut but struggles to cross fat-based cell membranes, especially in nerve tissue protected by myelin. Benfotiamine is a fat-soluble form that enters cells 3.6× more efficiently, delivering higher intracellular thiamine levels and supporting the energy pathways neurons rely on.

Brownlee M et al. · Hammes HP et al. · Multiple comparative bioavailability studies on Benfotiamine vs. thiamine HCl

Every ingredient in Omnium was chosen for the form that reaches your cells — not the form that reads best on a label. The full form rationale for all 27 ingredients is documented in each ingredient card below. See all ingredients →

THE LONG GAME

Building your foundation isn't just about feeling better today. The research connects it to how long you live.

The emerging longevity research doesn't point to exotic interventions or expensive biohacking. It consistently points to the same nutrients — the ones most Americans are already deficient in, at doses most supplements don't deliver.

4.7

lower risk of death from any cause in individuals with the highest vs. lowest Omega-3 blood levels, tracked over 14 years

Framingham Offspring Cohort · Am. J. Clinical Nutrition 2021

200+

genes regulated by Vitamin D — including those governing cellular aging, immune surveillance, and inflammation pathways

Voltan et al., Genes 2023 · PMC10531002

33%

lower risk of death from any cause in individuals with the highest vs. lowest Omega-3 blood levels, tracked over 14 years

OmegaQuant / Harris et al. · 14-year cohort · 2,600+ adults

An analysis of 117,000 participants linked higher DHA blood levels to significantly better long-term health outcomes — including cardiovascular wellness, cellular health, and overall longevity markers.

UK BIOBANK — 2024

This is the largest study of its kind — extending omega-3's documented benefits well beyond heart health into broader long-term wellness outcomes across all major categories studied.

Mayo Clinic Proceedings 2024 · n=117,000

A 2025 post-hoc analysis found that 1g/day of Omega-3 supplementation measurably slowed epigenetic aging markers over three years — with the effect strongest when combined with Vitamin D.

EPIGENETIC AGING — 2025

Epigenetic age is one of the most reliable measures of biological aging currently used in longevity research. This finding directly links the two most deficient nutrients in the US population to a slowdown in how fast the body ages at the molecular level.

Post-hoc analysis · Smith et al. 2025

The Omega-3 + Vitamin D synergy — built into Omnium

The 2025 epigenetic aging research found the slowdown in biological aging was strongest when Omega-3 and Vitamin D were taken together — not independently. Both are fat-soluble, both regulate gene expression, and both are among the most widespread deficiencies in the US population. Omnium delivers 700mg combined EPA+DHA and 5,000 IU D3 in the same daily system — the dose combination used in the research, built into your morning and evening packets.

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THE SCIENCE BEHIND EACH INGREDIENT

Every ingredient chosen with intention. Here's why.

Five of Omnium's most critical ingredients — each with a clinical diagram showing the mechanism, the form rationale, and the research behind the dose. Then explore all 27 below.

AM · TRACE MINERALS

Albion® Chelated Minerals

Zinc, Copper, Manganese, Molybdenum — bisglycinate chelate form

Most mineral supplements use inorganic salts — oxides, sulfates, carbonates. These forms are poorly absorbed, compete with each other for the same gut transporters, and bind to phytates in food before your body can absorb them. Albion® chelation solves all three problems simultaneously.

 

Why this form matters

Each mineral is covalently bonded to two glycine amino acids, creating a stable, electrically neutral molecule. The body transports it via dedicated amino acid channels — the same route used for food nutrients. The result is dramatically higher absorption with none of the GI side effects. Magnesium oxide absorbs at ~4%. Magnesium glycinate absorbs at 80%+.

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EVERY INGREDIENT

All 27. Every one chosen with intention.

Click any card to explore the full science — what the ingredient does, why this specific form, and the clinical research behind the dose. Every decision is documented.

☀ AM Packet — Methyl B-Complex

AM

B1

VITAMIN B1

Benfotiamine · 25mg

AM

B2

VITAMIN B2

Riboflavin-5'-P · 20mg

AM

B3

VITAMIN B3

Niacinamide · 75mg

AM

B6

VITAMIN B6

Pyridoxal-5'-P · 10mg

AM

F

FOLATE

5-MTHF · 400mcg DFE

AM

B12

VITAMIN B12

Methylcobalamin · 500mcg

AM

B

BIOTIN

300mcg · 1000% DV

AM

B5

Pantothenic Acid

D-Ca Pantothenate · 50mg

AM

I

Potassium Iodide · 200mcg

Iodine

AM

Zn

Albion® Chelate · 30mg

ZINC

AM

Se

L-Selenomethionine · 200mcg

Selenium

AM

Cu

Albion® Chelate · 2mg

Copper

AM

Mn

Albion® Chelate · 4mg

Manganese

AM

Cr

Polynicotinate · 200mcg

Chromium

AM

Mo

Albion® Chelate · 250mcg

Molybdenum

AM

K

Potassium Chloride · 100mg

Potassium

AM

B

Boron Citrate · 200mcg

Boron

AM

V

Bisglycinate Oxovanadium · 150mcg

Vanadium

AM

SiO₂

Horsetail Extract · 100mcg

Silica

☀ AM Packet — Trace Minerals

AM

C

VITAMIN C

Ascorbic Acid · 1000mg

AM

A

VITAMIN A

Retinyl Acetate · 600mcg RAE

AM

D3

VITAMIN D3

Cholecalciferol · 5000 IU

AM

E

Vitamin E

d-Alpha Tocopherol · 33.5mg

AM

K2

Vitamin K2 MK-4

Menaquinone-4 · 1000mcg

AM

K2

Vitamin K2 MK-7

Menaquinone-7 · 100mcg

☀ AM Packet — Vitamin C & ADEK

PM

EPA

EPA

Eicosapentaenoic Acid · 400mg

PM

DHA

DHA

Docosahexaenoic Acid · 300mg

PM

C

Chlorella

Broken Cell · 500mg

PM

MG

Magnesium

Glycinate · 133mg

☾ PM Packet — Omega-3, Chlorella & Magnesium

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This is what complete feels like.

The Complete Daily System

Two packets. 27 nutrients. The active forms your body can use, the clinical doses that support your foundation, and the timing that makes it all work.*

Shop The System
See The Science

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